Pyroluria - Why Still Overlooked?

Known by names such as Pyrrole disorder and Kryptopyroluria, this condition has been recognized for over 50 years. Despite its association with numerous psychological and physical health issues affecting society today, it continues to be largely overlooked by the global medical community.

But what exactly is it?

Currently, there is limited understanding; despite having good diets, the binding of B6, Zinc, Magnesium, Biotin, Manganese, Chromium, Omega 6/essential fatty acids, Lithium, Leucine, Isoleucine, and Valine often leads to deficiencies and related symptoms.and the flip side of this is poor methylation which results in extremely high levels of Copper, Mercury, Aluminium and other heavy metals.

Pyrroles are waste compounds produced during hæmoglobin formation and are typically eliminated through urine. However, various factors such as a toxic environment, damage from pharmaceutical drugs, injury, and stress can lead to an excessive production of pyrroles, which the body struggles to excrete. This results in depleted enzyme and hormone levels, leading to severe consequences. Instead of addressing the root cause, the resulting conditions often become standalone diagnoses. So, what are the symptoms?

In reality, nearly any mental health or neurological disorder, autoimmune disorder, or chronic health condition could be associated with pyroluria, if not directly causing it:

• Neurological disorders include PANDAS, autism, bipolar disorder, ADHD, Tourette's syndrome, schizophrenia, sensory disorders, criminal behavior, psychosis, manic depression, dyslexia, and PTSD.

• Endocrine disorders, including thyroid and adrenal issues, elevated cortisol levels, and irregular fat distribution,

• Autoimmune disorders such as chronic fatigue, MS, fibromyalgia, lyme, mould sensitivity, Parkinsonism, Alzheimers - and more

• Gut/Microbiome - candida, leaky gut, SIBO, food intolerances,

• Chromosomal disorders - Down Syndrome, macular degeneration, addictive personality

• Hormonal - Post natal depression, diabetes, delayed puberty

• Skin & hair - eczema, dermatitis, psoriasis, lupus, acne, dry skin, premature grey hair, hypopigmentation of skin, inability to tan, absence or reduction in eyelashes and brows

• Connective tissue - crowding of teeth, weak tooth enamel, weak muscles, rashes, stretchmarks, stunted growth, dental cavities, receding gums, excessive white spots on fingernails

• Other known issues include - Cancers, criminal behaviour, allergies, epilepsy, poor immunity, amenorrhoea or irregular periods, splenomegaly

Everyday symptoms may include:

• Migraines

• Always feeling sick

• Phobias

• Mood swings

• Fluctuating blood sugar

• Insomnia

• Food sensitivities

• Poor wound healing

• Fatigue

• Constant infections

Possible causes or triggers:

• Genetic tendency

• Pathogenic trigger (EB, bacterial infection etc)

• IUD or other high copper exposure

• Abuse & trauma triggers

• Unhealthy diet & lifestyle

• Toxic liver

• Exposure to toxic chemicals

• Heavy metals (low enzyme levels = reduced heavy metal detoxification)

So what is the treatment?

Treatment options and their effectiveness differ greatly because many healthcare professionals do not recognize the issue, opting instead for pharmaceuticals that only hide symptoms or cause additional ones, or for synthetic supplements that hinder the body's natural functions.

Undoubtedly, plant-based, pure supplements like zinc, B6, biotin, magnesium, and manganese are essential (refer to the list above), but the most crucial steps are detoxifying heavy metals, altering one's diet, and eliminating exposure to toxic environments.

Homeopathic healing is another method of dealing with symptoms without simply masking them. Certain remedies assist with the symptoms while others help reduce heavy metals. Symptomatically, gentle assistance with anxiety are often needed, while symptoms such as feelings that overwhelm (panic, fear, extreme responses) can be dealt with while avoiding the need to sedate. Those who self-medicate with addictions or develop addictive personalities may find support here while an overall medicinal mushroom tonic can assist in balance. For more symptoms of concern please either consider the online consultation or send an email.

REFERENCES:

More on Pyroluria

Integrative psychiatry view

Testing of pyrrole disorder